Association Between Component-Resolved Diagnosis of House Dust Mite Allergy and Efficacy and Safety of Specific Immunotherapy
نویسندگان
چکیده
منابع مشابه
Immunotherapy of house dust mite allergy
House dust mite (HDM) is a predominant source of indoor aeroallergen worldwide, which induces allergic diseases including allergic rhinoconjunctivitis, allergic asthma, atopic eczema and other allergic skin diseases. Allergen specific immunotherapy (AIT) is the only potential disease-modifying treatment of HDM allergic subjects. However, AIT remains underused due to no universally accepted alle...
متن کاملHouse dust mite allergy
The importance of the allergens in sensitisation and disease can be readily demonstrated in regions with and without mite infestation. Dose-responce relationships in regions with high infestation are less easy to detect pointing to the importance of variations of other factors. The relationship between allergic disease and IgE antibody shows that only people with very high responses become pers...
متن کاملHouse dust allergy and immunotherapy
HDM allergy is associated with asthma, allergic rhinitis and atopic dermatitis. In many countries childhood asthma is predominantly found in HDM-allergic children with their probability of developing disease being proportional to their IgE antibody titers and the early development of Th2 responses. While the pathogenesis is complex and increasingly linked to infection the immunologically-based ...
متن کاملDiagnosis of nasal allergy to the house dust mite.
Twenty-five patients with perennial rhinitis and a positive skin prick test (SPT) for Dermatophagoides pteronyssinus (Dp) and Dermatophagoides farinae (Df) were submitted to nasal provocation and the radioimmunosorbent test (RAST) for specific IgE-antibodies. We found a significant correlation in the reaction to both allergen extracts for all parameters examined. In addition, there was a signif...
متن کاملHouse Dust Mite Allergy and Associated Allergen-Specific Immunotherapy in Allergic Asthma
There is an increasing trend in the global prevalence, morbidity, and economic burden associated with asthma in recent decades [1]. The Global Strategy for Asthma Management and Prevention Report [2] defined asthma as a chronic inflammatory disorder of the airways in which many cells and cellular elements are involved. Both host factors (primarily genetic) and environmental factors (primarily a...
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ژورنال
عنوان ژورنال: Journal of Investigational Allergology and Clinical Immunology
سال: 2019
ISSN: 1018-9068
DOI: 10.18176/jiaci.0359